Prolonged neonatal myocardial preservation with a highly buffered low-calcium solution
نویسندگان
چکیده
منابع مشابه
Superior myocardial preservation with HTK solution over Celsior in rat hearts with prolonged cold ischemia.
BACKGROUND Increasing allograft ischemic time is a significant risk factor for mortality following heart transplantation (HTx). The purpose of this study was to evaluate the protective effects of histidine-tryptophan-ketoglutarate (HTK) and Celsior (CEL) using a rat HTx model with prolonged cold storage. METHODS The hearts were excised from donor rats, stored in cold preservation solution for...
متن کاملProlonged rat cardiac preservation with UW lactobionate solution.
T HE MOST significant limiting factor in the further expansion of clinical cardiac transplantation consists of the availability of suitable donors and the duration of viability of the organ following harvest. Currently, the safe limits of static cold cardiac preservation are considered to be four to six hours using the standard Stanford preservation solution as listed in Table 1. Belzer and col...
متن کاملCalcium-supplemented University of Wisconsin solution in long-term myocardial preservation.
The purpose of this study was to assess the effects of the addition of calcium to University of Wisconsin solution in long-term myocardial perfusion. In a heterotopic heart transplantation model, performed in pigs, the donor heart was preserved for 24 hours by means of continuous perfusion in this solution, without (24hUW group) or with calcium, 2.4 mmol/L (24hUW+Ca). During this period, the ox...
متن کاملClinical assessment of prolonged myocardial preservation for patients with a severely dilated heart.
BACKGROUND The purpose of this study was to compare the myocardial protective effect of histidine-tryptophan-potassium and glucose-insulin-potassium cardioplegic solutions in patients with a dilated heart (left ventricular diastolic diameter > 55 mm, left ventricular systolic diameter > 45 mm) associated with prolonged cross-clamp time (longer than 200 minutes). METHODS We selected 20 patient...
متن کاملPreservation of Neonatal Myocardial Function Following Ischemic Arrest
The protection of the ischemic neonatal myocardium was studied utilizing both cardioplegic and noncardioplegic solutions. Six groups of seven-day-old isolated working rabbit hearts, exposed to 120 minutes of hypothermic (3()oC) arrest, were treated with either an oxygenated or nonoxygenated cardioplegic or physiologic saline solution. The results indicated that postischemic aortic flow, stroke ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1994
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(94)70306-x